N-Terminal Pro-B-Type Natriuretic Peptide (NT-proBNP)
PDB ID: 1YK1. Source: RCSB Protein Data Bank. For illustration purposes only.
VeriLumenTM N末端前B型利钠肽原
The VeriLumenTM NT-proBNP Rapid Test is a fluorescence immunochromatographic assay for the quantitative detection of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in human whole blood, plasma, or serum samples. NT-proBNP is an inactive cleavage fragment released from proBNP in parallel with BNP in response to ventricular wall stress and volume overload. It is widely used in the clinical evaluation of heart failure and provides complementary information to BNP measurement. The assay provides rapid quantitative results to support timely clinical assessment in laboratory and point-of-care settings.
NT-proBNP is commonly used in structured diagnostic and laboratory-based evaluation of heart failure, particularly where standardized measurement and longer analyte stability are preferred. It is frequently applied in centralized laboratory workflows and supports diagnostic assessment and risk evaluation in patients with suspected heart failure. Quantitative NT-proBNP measurement supports clinical evaluation when interpreted together with clinical findings and other diagnostic information.
| Ref. Code | 808166 |
| Analyte | N-Terminal Pro-B-Type Natriuretic Peptide (NT-proBNP) |
| Format | Fluorescence lateral flow immunoassay (cassette format) |
| Diagnostic Readout | Quantitative |
| Time to Result | 10 minutes |
| Detection Range | 20–35000 pg/mL |
| Reference Value | < 75 years: 0–300 pg/mL≥ 75 years: 0–450 pg/mL | R2 | ≥ 0.95 |
| Storage Conditions | 2–30°C |
| Shelf Life | 18 months |
| Certificate | CE, NMPA |
| Sample Types | Human whole blood, plasma or serum |
| Sample Volume | 100μL |
| Collection Method | Venous blood |
| Sample Stability | Stable for testing within 1 hour at room temperature (as validated) |
| Acceptable Anticoagulants | EDTA / Heparin / Citrate (as applicable) |
| Notes on Handling | Specimens should be collected and handled using standard laboratory procedures. Use fresh samples when possible and avoid hemolyzed, lipemic, or contaminated specimens. |
| Detection Method | Quantitative fluorescence immunochromatography |
| Antibody Format | Monoclonal / sandwich |
| Signal Generation | Fluorescence signal (fluorescent-labeled immunochromatography) |
| Reading Method | Instrument-based |
| Mechanism | The assay is based on a fluorescence immunochromatographic sandwich principle, in which N-terminal pro-B-type natriuretic peptide (NT-proBNP) present in the sample binds to specific fluorescently labeled anti–NT-proBNP antibodies during capillary migration along the membrane. The resulting antigen–antibody complexes are captured by immobilized antibodies at the test region, and the fluorescence signal is measured and correlated with the NT-proBNP concentration in the specimen. |
| Tests per Kit | 10/25/50 Tests |
| Dimension of Kit Box | 21 × 13.5 × 8 cm |
| Kits per Carton | 48 Kits |
| Tests per Carton (Bulk) | 1200 Tests |
| G.W. per Carton (Boxed) | 23.2 kg |
| G.W. per Carton (Bulk) | 26.2 kg |
| Carton Dimension | 67 × 57.5 × 39 cm |
| Carton Volume | 0.15 CBM |
| Packaging Format | Individual sealed test kits / bulk configuration (as applicable) | Items Included | - Test cassette - Desiccant- Sample diluent- ID chip- Instructions for Use |
| Storage & Shipping Conditions | Standard ambient transport; store according to product label requirements |
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